|
 |
| |
| Fenticonazole nitrate BP2011 |
Product name: Fenticonazole nitrate BP2011
Molecular formula: C24H20Cl2N2OS,HNO3
Molecular weight: 518.4
Cas NO.: 73151-29-8
Content: 99.0-101.0
Appearance: white or almost white crystal powder
Solubility: nearly insoluble in water and easily soluble in dimethylformamide, methyl alcohol and ethyl alcohol
Identification:
A. melting point 134°C to 137°C.
B. ultraviolet
C. infrared
Testing
optical rotation- 0.10 °to + 0.10°.
Relative substance
— impurity: A, B, C, D, E: (0.2%);
—total impurity: (0.5%);
— Other impurity: 0.05%
methylbenzene: 100 ppm.
loss on drying: 0.5 %
sulphated ash: 0.1 %
Impurity
Specified impurities A, B, C, D, E.
A. (RS)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol,
B. X = SO: 1-[(2RS)-2-(2,4-dichlorophenyl)-2-[[4-(phenylsulfinyl)benzyl]oxy]ethyl]-1H-imidazole,
C. X = SO2: 1-[(2RS)-2-(2,4-dichlorophenyl)-2-[[4-(phenylsulfonyl)benzyl]oxy]ethyl]- 1H-imidazole,
D. (RS)-1-[2-(2,4-dichlorophenyl)-2-hydroxyethyl]-3-[4- (phenylsulfanyl)benzyl]imidazolium nitrate,
E.(RS)-1-[2-(2,4-dichlorophenyl)-2-[4-(phenylsulfanyl)benzyloxy]ethyl]-3-[4- (phenylsulfanyl)benzyl]imidazolium nitrate.
Ph Eur |
| |
